Low dose effects and non-monotonic dose responses for endocrine active chemicals: Science to practice workshop: Workshop summary

TitleLow dose effects and non-monotonic dose responses for endocrine active chemicals: Science to practice workshop: Workshop summary
Publication TypeJournal Article
AuthorsBeausoleil, Claire, Jean-Nicolas Ormsby, Andreas Gies, Ulla Hass, Jerrold J. Heindel, Marie Louise Holmer, Pia Juul Nielsen, Sharon Munn, and Gilbert Schoenfelder
JournalChemosphere
Volume93
Issue6
Pagination847-856
ISSN0045-6535
AbstractA workshop was held in Berlin September 12–14th 2012 to assess the state of the science of the data supporting low dose effects and non-monotonic dose responses (“low dose hypothesis”) for chemicals with endocrine activity (endocrine disrupting chemicals or EDCs). This workshop consisted of lectures to present the current state of the science of EDC action and also the risk assessment process. These lectures were followed by breakout sessions to integrate scientists from various backgrounds to discuss in an open and unbiased manner the data supporting the “low dose hypothesis”. While no consensus was reached the robust discussions were helpful to inform both basic scientists and risk assessors on all the issues. There were a number of important ideas developed to help continue the discussion and improve communication over the next few years.
URLhttp://www.sciencedirect.com/science/article/pii/S0045653513008850
DOI10.1016/j.chemosphere.2013.06.043
Short TitleLow dose effects and non-monotonic dose responses for endocrine active chemicals